Recurrence Risk Prediction

Pre Conception

Will it happen again?

The prediction of recurrence risk of the problem – This is very important for most families so that they can decide whether to try for further pregnancies and what methods to adopt for the achievement of a successful pregnancy. There are different modes / patterns of inheritance (autosomal dominant, autosomal recessive, sex-linked, mitochondrial, etc). So depending on step 1 and 2, the specialist can predict the chances of the condition happening again. In some cases, the condition needs the use of complex technology to achieve a successful pregnancy, while in most cases, this is not necessary.

Has the condition recurred / occurred in this pregnancy?

Prenatal Diagnosis – Most conditions can be detected by procedures carried out early in the pregnancy (by 11-12 weeks) so that the diagnosis can be made early in the pregnancy. This allows sufficient time for decisions to be taken by the family regarding continuation / termination of pregnancy.

However, some syndromes may need to be detected by detailed ultrasound scanning as the genetic mutation /basis may not have been detected.

Prenatal diagnosis involves procedures like chorionic villous sampling (CVS), amniocentesis and ultrasound scans.

What do we do next if the condition has recurred?

You need to be referred to a Fetal Medicine Specialist who can guide you through the above steps and check whether all these have been followed correctly. The most important steps are 1 and 2.